Biochemical effects of extracts of fruits of cornelian cherry (Cornus mas L.) under experimental 1 type diabetes mellitus.

Articles:

1. Moroz A., Brodyak I., Kucharska A. Z., Sybirna N. Anaerobic glycolysis and oxidative stress interrelation in erythrocytes under administration of Сornus mas L. fruit extracts to rats with streptozotocin-induced diabetes mellitus. Studia Biologica. 2024. Vol. 18, № 2. P. 49–66. https://doi.org/10.30970/sbi.1802.777.
2. Brodyak І.V., Мoroz А. А., Kucharska A. Z., Sybirna N. О. Fruit extracts of various cornelian cherry (Cornus mas L.) cultivars as antioxidant therapy for alleviating nitrative stress in erythrocytes of blood in experimental diabetes. Current issues in pharmacy and medicine: science and practice. 2024. Vol. 17, № 2(45). P. 154–159. https://doi.org/10.14739/2409-2932.2024.2.301202.
3. Brodyak I. V., Chaban M. O., Moroz A. A., Kucharska A. Z., Sybirna N. O. The effect of extracts of fruits of different cultivars of Сornus mas L. on plasma lipid profile in experimental diabetes mellitus. Studia Biologica. 2023. Vol. 17, № 1. P. 35–48. http://dx.doi.org/10.30970/sbi.1701.704.
4. Moroz A., Peretyatko T., Brodyak I., Sybirna N. Antibacterial and antifungal activity iridoid glycoside – loganic acid extracted from yellow fruits of cornelian cherry (Cornus mas L.) // Prospective directions of scientific research of medical and essential oil cultures: V All-Ukrainian scientific and practical conference of young scientists (Berezotocha, March 25, 2022) /RSMP IANM NAAS.– Lubny “Inter Park”, 2022. P. 84–87.
5. Moroz A., Peretyatko T., Brodyak I., Kucharska A. Z., Sybirna N. Antimicrobial activity of biologically active compounds of extracts of fruits of cornelian cherry (Cornus mas L.) // Medical plants: traditions and prospects of research: materials of the 5th international scientific conference (Berezotocha, April 2, 2021) /RSMP IANM NAAS.– Lubny “Inter Park”, 2021. P. 293–296.
6. Moroz A., Seniv M., Dzydzan O., Brodyak I., Sybirna N. Changes in differential leukocyte count of rats with streptozotocin-induced diabetes by administration of loganic acid and extracts of red and yellow fruits of cornelian cherry (Cornus mas L.) // Prospective directions of scientific research of medical and essential oil crops: materials of the 4th All-Ukrainian scientific and practical conference of young scientists (Berezotocha, March 25, 2020) /RSMP IANM NAAS.– Lubny “Inter Park”, 2020. P. 228–232.

Abstracts:

1. Moroz A., Naum J., Lomov A., Brodyak I., Kucharska А. Z., Sybirna N. Effect of the fruit extract of cornelian cherry of the ‵Uholok′ cultivar on the erythrocytes of blood in streptozotocin-induced diabetes mellitus. “Youth and progress of biology”: ХХ International scientific conference for students and PhD students, dedicated to the 90th anniversary from the birthday of professor O. Demkiv, April 18–20, 2024: Abstracts. Lviv, 2024. P. 63–64.
2. Lomov A., Naum J., Moroz A., Brodyak I., Kucharska А. Z., Sybirna N. Effect of fruit extract of Сornus mas L. & Cornus officinalis Siebold & Zucc. on blood glucose profile and erythrocytes of rats with streptozotocin-induced diabetes mellitus. “Youth and progress of biology”: ХХ International scientific conference for students and PhD students, dedicated to the 90th anniversary from the birthday of professor O. Demkiv, April 18–20, 2024: Abstracts. Lviv, 2024. P. 87–88.
3. Shtabska J., Uruska M., Moroz A., Brodyak I., Kucharska А. Z., Sybirna N. Difference on glucose profile in rats with streptozotocin diabetes vs. Cornelian cherry-treated diabetic groups. “Youth and progress of biology”: ХХ International scientific conference for students and PhD students, dedicated to the 90th anniversary from the birthday of professor O. Demkiv, April 18–20, 2024: Abstracts. Lviv, 2024. P. 90–91.
4. Trach Y., Moroz A., Brodyak I., Kucharska А. Z., Sybirna N. Alteration of protein metabolism in experimental diabetes mellitus after oral administration of fruit extracts of different cultivars of Cornus mas L. and hybrid Cornus mas × Cornus officinalis. “Youth and progress of biology”: ХХ International scientific conference for students and PhD students, dedicated to the 90th anniversary from the birthday of professor O. Demkiv, April 18–20, 2024: Abstracts. Lviv, 2024. P. 103–104.
5. Moroz A., Brodyak I., Kuсharska A., Sybirna N. Indicators of nitrative stress in blood erythrocytes as biomarkers of the development of diabetes mellitus in rats under the administration of fruit extracts of different cultivars of Cornus mas L. VIII International scientific and practical conference “Ternopil biological readings – Ternopil bioscience – 2024”, dedicated to the 95th anniversary of the birth of K. M. Vekirchyk, April 18-19, 2024: Abstracts. Ternopil, 2024. P. 179–181.
6. Moroz A., Brodyak I., Kuсharska A., Sybirna N. Metabolism of nitrogen oxide in the body under the administration the extracts of red and yellow fruits of cornelian cherry (Cornus mas l.) in animals with streptozotocin-induced diabetes mellitus // // Prospective directions of scientific research of medical and essential oil cultures: VI All-Ukrainian scientific and practical conference of young scientists (Berezotocha, March 25, 2024) /RSMP IANM NAAS– Кyiv: “KOMPRINT Printing Center”, 2024. P. 163–166. https://doi.org/10.5281/zenodo.11119087.
7. Moroz A., Brodyak I., Kuсharska A., Sybirna N. The effect of the extract of the hybrid fruits of Сornus mas L. & Cornus officinalis Siebold & Zucc.on the functional state of erythrocytes under diabetes mellitus. I International scientific and practical online conference “Modern achievements of experimental, clinical, environmental biochemistry and molecular biology”, dedicated to the 85th anniversary of the department of biochemistry, March 7, 2024 : Abstracts. Kharkiv, 2024. P. 526 – 528.
8. Moroz A., Chaban M., Brodyak I., Kucharska A. Z., Sybirna N. Plasma lipid profile in experimental diabetes mellitus under oral administration of extracts of fruits of different cultivars of Cornus mas“Youth and progress of biology”: XIX International scientific conference for students and PhD students, dedicated to the 90th anniversary from the birthday of academician of NAS of Ukraine, prof. Y. R. Shelyag-Sosonka, April 26–28, 2023 : Abstracts book. Lviv, 2023. P. 47–48.
9. Moroz A., Brodyak I., Kucharska A. Z., Sybirna N. The effect of extracts of fruits of different cultivars of cornelian cherry (Cornus mas L.) on the glucose concentration, the level of lactate and pyruvate in rats’ blood plasma under streptozotocin-induced diabetes mellitus. “Youth and progress of biology”: XIX International scientific conference for students and PhD students, dedicated to the 90th anniversary from the birthday of academician of NAS of Ukraine, prof. Y. R. Shelyag-Sosonka, April 26–28, 2023 : Abstracts book. Lviv, 2023. P. 32–33.
10. Moroz A., Chaban M., Naum Yu., Lomov A., Brodyak I., Kucharska A. Z., Sybirna N. O. The state of the erythron system in experimental diabetes and under oral administration of extract of fruits of the “Koralovyi” cultivars of Cornus mas XXI All-Ukrainian scientific and practical conference of young scientists, dedicated to the 100th anniversary of the birthday of doctor of biological sciences, prof. Shavkun V. Yu., May 18–19, 2023: Abstracts book. Lviv, 2023. P. 68.
11. Moroz A., Peretyatko T., Brodyak I., Kucharska A. Z., Sybirna N. Antimicrobial evaluation of fruit extract from cornelian cherry (Cornus mas) “Youth and progress of biology: XVIІI International scientific conference for students and PhD students, dedicated to the 195th anniversary from the birthday of Julius Planer ”, October 6–7, 2022 : Abstracts book. Lviv, 2022. P. 36–37.
12. Moroz A., Chaban M., Brodyak I., Sybirna N. Correction of phagocytic activity of leukocytes by extracts of Cornus mas fruits under experimental diabetes mellitus. Actual problems of modern biochemistry, cell biology and physiology: materials of the VI International Scientific Conference, October 6–7, 2022, Dnipro, Ukraine / by general ed. Ushakova G.O. – Dnipro: “Lira”, 2022. P. 86–87.
13. Chaban M., Moroz A., Brodyak I., Kucharska A., Sybirna N. The effect of loganic acid on glycemic profile indicators and the activity of aminotransferases in blood plasma of rats with streptozotocin-induced diabetes mellitus. Actual problems of modern biochemistry, cell biology and physiology: materials of the VI International Scientific Conference, October 6–7, 2022, Dnipro, Ukraine/ by general ed. Ushakova G.O. – Dnipro: “Lira”, 2022. P. 48–49.
14. Моroz А., Peretyatko Т., Brodyak І., Kucharska A. Z., Sybirna N. Antimicrobial effect of the extracts of red and yellow fruits of cornelian cherry (Cornus mas L.). “Youth and the progress of biology”: XVIІ International Scientific Conference of Students and PhD Students. Lviv, April 19–21 : Abstracts book. Lviv, 2021. Р. 194–195.
15. Moroz A., Dzydzan O., Brodyak I., Kucharska А. Z., Sybirna N. Effect of purple potato extract of the Blue Congo variety on the markers of oxidative stress in rats’ blood leukocytes under streptozotocin-induced diabetes mellitus. “Youth and progress of biology”: XVI International scientific conference for students and PhD students, dedicated to the 75th anniversary of the Faculty of Biology of Ivan Franko National University of Lviv and 90th anniversary from the birthday of prof. M. P. Derkach, April 27–29, 2020 : Abstracts book. – Lviv, 2020. – P. 30–31.
16. Kalanova S., Moroz A., Seniv M., Dzydzan O., Kucharska A. Z., Brodyak I., Sybirna N. Effect of extract of red fruits of cornelian cherries (Cornus mas L.) оn the activity of antioxidant defence enzymes in rat’s red blood cells with streptozotocin-induced diabetes mellitus. “Youth and progress of biology”: XVI International scientific conference for students and PhD students, dedicated to the 75th anniversary of the Faculty of Biology of Ivan Franko National University of Lviv and 90th anniversary from the birthday of prof. M. P. Derkach, April 27–29, 2020 : Abstracts book. – Lviv, 2020. – P. 42.
17. Dzydzan O., Moroz A., Seniv M., Kucharska A., Brodyak I., Sybirna N. Effect of iridoids and anthocyanins from the Cornus mas L. fruits on the antioxidant defense system in leukocytes under experimental diabetes mellitus. The Fifth International scientific Conference “Аctual problems of biochemistry, cell biology and physiology”, October 1–2, 2020 : Abstracts book. Dnipro, 2020. Р. 95–96.

The date of birth: December 22, 1998 (Lviv)

2022 – present  – PhD student at the Department of Biochemistry, Biological Faculty of Ivan Franko National University of Lviv.

2020 –  2021 – Master student of the Faculty of Biology of Ivan Franko National University of Lviv.

2016 – 2020 – Bachelor student of the Faculty of Biology of Ivan Franko National University of Lviv.

2005 – 2016  – Schoolgirl of V. Chornovol Secondary School № 46 with in-depth study of English language of Lviv.

Individual grant from the Polish National Agency for Academic Exchange (Jagiellonian University, Krakow, Poland) for an academic visit and participation in the conference “The conference on stem cells for disease modeling and therapy“, which passed at the Faculty of Biochemistry, Biophysics and Biotechnology at the Jagiellonian University in Krakow from November 29 to 30, 2023 and was organized as part of the Una4UA project.

Individual grant from the Polish National Agency for Academic Exchange (Jagiellonian University, Krakow, Poland) for an academic visit and participation in the conference “Paths to frontier research: what is just Starting at the Jagiellonian University“, which passed at the Faculty of Biochemistry, Biophysics and Biotechnology at the Jagiellonian University University in Krakow from June 25 to 28, 2023 and was organized as part of the Una4UA project.

2024 – certificate of completion of the cycle of training seminars “Safe and healthy working environment under martial law” (30 hours) from Ivan Franko Lviv National University, Lviv, Ukraine.

2023 – certificate of attendance in the Summer School for postgraduate and doctoral students “Novel analytical methods in chemical analysis and forensic genetics” (100 hours) from the Center for Biological and Chemical Research of the University of Warsaw, Warsaw, Poland.

2023 – certificate of attendance in the conference “Paths to frontier research: what is just Starting at the Jagiellonian University”, organized as a part of the Una4UA Project, Krakow, Poland.

2023  – 3^rd Prize for Oral Presentation in Section “Biochemistry” in XIX International scientific conference for students and PhD students “Youth and progress of biology, dedicated to the 90th anniversary from the birthday of academician of NAS of Ukraine, prof. Y. R. Shelyag-Sosonka” , Lviv, Ukraine.

2022 – 2^nd Prize for Oral Presentation in Section “Biochemistry” in XVIII International scientific conference for students and PhD students “Youth and progress of biology, dedicated to the 195th anniversary from the birthday of Julius Planer”, Lviv, Ukraine.

2021–2022 – certificate of attendance in the Summer School of the Department of Biochemistry for students and PhD students “Functional food products – new challenges of balanced nutrition and treatment of metabolic disorders”, organized as a part of the ResBios project, Lviv, Ukraine.

2021 – 1^st Prize for Oral Presentation in Section “Microbiology, immunology and virology” in XVII International scientific conference for students and PhD students “Youth and progress of biology”, Lviv, Ukraine.

2021 – certificate of successful completion of the 20-hour course of the Educational Program on the Development of Personal and Professional Communications “With Experience for the Future” of the joint-stock company “Galychpharm”, Lviv, Ukraine.

2020 – 3^rd Prize for Oral Presentation in Section “Biochemistry” in XVI International scientific conference for students and PhD students “Youth and progress of biology, dedicated to the 75th anniversary of the Faculty of Biology of Ivan Franko National University of Lviv and 90th anniversary from the birthday of prof. M. P. Derkach” , Lviv, Ukraine.